Chromosomal abnormalities & oxidative stress in women with premature ovarian failure (POF)
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چکیده
منابع مشابه
Chromosomal abnormalities & oxidative stress in women with premature ovarian failure (POF)
BACKGROUND & OBJECTIVES Premature ovarian failure (POF) is defined as the cessation of ovarian function under the age of 40 yr and is characterized by amenorrhoea, hypoestrogenism and elevated serum gonadotrophin levels. The cause of POF remains undetermined in majority of the cases. This study was aimed to investigate the type and frequency of cytogenetic abnormalities in patients with idiopat...
متن کاملBeneficial Effects of Tibolone on Sexual Dysfunction in Women with Premature Ovarian Failure (POF)
Introduction: Premature Ovarian Failure (POF) is cessation of ovarian functions before the age of 40 years old with consequent cessation of menstruation. Objective of study: The aim of this study was to evaluate the association between Premature Ovarian Failure and sexual dysfunctions and outcome of management with tibolone. Patients and Methods: Thirty-one women with Premature Ovarian Failure ...
متن کاملScreening of FSH receptor gene in Argentine women with premature ovarian failure (POF).
Diverse mutations in FSH-receptor (FSHR) gene have been described as possible cause of premature ovarian failure (POF). To investigate the presence of mutations and/or polymorphisms in FSHR gene, DNA from 20 POF, 5 of which were diagnosed as resistant ovary syndrome (ROS), and from 44 controls was isolated from peripheral lymphocytes. The complete coding sequence was analysed by PCR followed by...
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PURPOSE Women with epilepsy (WWE) have an increased risk for several reproductive endocrine disorders that may affect their fertility. The incidence of premature ovarian failure (POF) in women with epilepsy has not been systematically studied. This study examined the incidence of POF in women with epilepsy. METHODS Fifty consecutively evaluated cognitively normal women with epilepsy, aged 38-...
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Premature ovarian failure (POF) is a heterogeneous disorder, defined as menopause under age 40 years. The prevalence is 1%; POF before age 30 years is much less common. Chromosomal causes have long been recognized - visible deletions of the X chromosome, 45,X/46,XX mosaicism, and autosomal rearrangements (balanced translocations). Toxins or iatrogenic causes (e.g., chemotherapeutic agents) are ...
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ژورنال
عنوان ژورنال: The Indian Journal of Medical Research
سال: 2012
ISSN: 0971-5916
DOI: 10.4103/0971-5916.93430